Endocrine Pharmacology
Publications list
Publications list
2011
Dhayal S, Morgan NG. 2011. Structure-activity relationships influencing lipid-induced changes in eIF2α phosphorylation and cell viability in BRIN-BD11 cells. FEBS Lett. Jul 21;585(14):2243-8.
Willcox A, Richardson SJ, Bone AJ, Foulis AK, Morgan NG. 2011. Immunohistochemical analysis of the relationship between islet cell proliferation and the production of the enteroviral capsid protein, VP1, in the islets of patients with recent-onset type 1 diabetes. Diabetologia. Sep;54(9):2417-20.
Dhayal S, Morgan NG. 2011. Pharmacological characterization of the cytoprotective effects of polyunsaturated fatty acids in insulin-secreting BRIN-BD11 cells. Br J Pharmacol. Mar;162(6):1340-50.
Immunopathology of the human pancreas in type-1 diabetes. 2011. Richardson SJ, Willcox A, Bone AJ, Morgan NG, Foulis AK. Semin Immunopathol. 33(1):9-21.
Russell MA, Morgan NG. 2011. Conditional expression of the FTO gene product in rat INS-1 cells reveals its rapid turnover and a role in the profile of glucose-induced insulin secretion. Clin Sci (Lond). 120(9):403-13.
2010
Dhayal S, Morgan NG. 2010. The significance of GPR119 agonists as a future treatment for type 2 diabetes. Drug News Perspect. 23(7):418-24.
Russell MA, Morgan NG. 2010. Expression and functional roles of guanylate cyclase isoforms in BRIN-BD11 β-cells. Islets. 2(6):374-82.
Richardson SJ, Willcox A, Hilton DA, Tauriainen S, Hyoty H, Bone AJ, Foulis AK, Morgan NG. 2010 Use of antisera directed against dsRNA to detect viral infections in formalin-fixed paraffin-embedded tissue.J Clin Virol. 49(3):180-5.
Willcox A, Richardson SJ, Bone AJ, Foulis AK, Morgan NG. 2010 Evidence of increased islet cell proliferation in patients with recent-onset type 1 diabetes. Diabetologia. 53(9):2020-8.
Morgan NG, Dhayal S. 2010 Unsaturated fatty acids as cytoprotective agents in the pancreatic beta-cell. Prostaglandins Leukot Essent Fatty Acids. 82(4-6):231-6.
2009
Morgan NG, Dhayal S. 2009 G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta-cell. Biochem Pharmacol. 78(12):1419-27.
Kaminski A, Welters HJ, Kaminski ER, Morgan NG. 2009 Human and rodent pancreatic beta-cells express IL-4 receptors and IL-4 protects against beta-cell apoptosis by activation of the PI3K and JAK/STAT pathways. 2009. Biosci Rep. 30(3):169-75.
Morgan NG, Diakogiannaki E, Russell MA. 2009. The incubation and monitoring of cell viability in primary rat islets of Langerhans and pancreatic beta-cell lines. Methods Mol Biol. 560:53-64.
Willcox, A., Richardson, S.J., Bone, A.J., Foulis, A.K. and Morgan, N.G. 2009. Analysis of islet inflammation in human type 1 diabetes. Clin. Exp. Immunol. 155, 173-181.
Morgan, N.G. 2009. Fatty acids and β-cell toxicity. Curr. Opin. Clin. Nutr. Metab. Care. 12, 117-122.
Richardson, S.J., Willcox, A., Bone, A.J., Foulis, A.K. and Morgan, N.G. 2009. The prevalence of enteroviral capsid protein, vp1, immunostaining in pancreatic islets in human type 1 diabetes. Diabetologia. 52, 1143-1151.
Morgan, N.G., Diakogiannaki, E. and Russell, M.A. 2009. The incubation and monitoring of cell viability in primary rat islets of Langerhans and pancreatic β-cell lines. Meth. Molec. Biol. 560, 53-64.
Richardson, S.J., Willcox, A., Bone, A.J., Foulis, A.K. and Morgan, N.G. 2009. Islet associated macrophages in type 2 diabetes. Diabetologia. 52, 1686-1688.
Kaminski, A., Welters, H.J., Kaminski, E.R. and Morgan, N.G. 2009. Human and rodent pancreatic β-cells express IL-4 receptors and IL-4 protects against β-cell apoptosis by activation of PI-3-kinase and Jak/STAT pathways. Biosci. Rep. In press.
Morgan, N.G. and Dhayal, S. 2009. G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta cell. Biochem. Pharmacol. 78, 1419-1427.
2008
Dhayal, S., Welters, H.J. and Morgan, N.G. 2008. Structural requirements for the cytoprotective actions of mono-unsaturated fatty acids in the pancreatic β-cell line, BRIN-BD11. Br. J. Pharmacol. 153, 1718-1727.
Farn, R.D., Morgan, N.G. and Ramsden, C.A. 2008. Preparation of Analogues of Efaroxan and KU14R as Potential I3 Imidazoline Receptor Ligands. J Heterocyclic Chem. 45, 887-896.
Welters, H.J., Oknianska, A., Erdmann, K.S., Ryffel, G.U. and Morgan, N.G. 2008. The protein tyrosine phosphatase, PTP-BL, modulates pancreatic β-cell proliferation by interaction with the Wnt signalling pathway. J. Endocrinol. 197, 543-552.
Diakogiannaki, E., Welters, H.J. and Morgan, N.G. 2008. Differential regulation of the endoplasmic reticulum stress response in pancreatic β-cells exposed to long chain saturated and mono-unsaturated fatty acids. J. Endocrinol. 197, 553-563.
Morgan, N.G., Dhayal, S., Diakogiannaki, E. and Welters. H.J. 2008. The cytoprotective actions of long chain mono-unsaturates in pancreatic β-cells. Biochem. Soc. Trans. 36, 905-908.
Diakogiannaki, E. and Morgan, N.G. 2008. Regulation of the ER stress response by long chain fatty acids in the pancreatic β-cell. Biochem. Soc. Trans. 36, 959-962.